INVESTIGATION OF ANTIMICROBIAL EFFECT OF DECASAN CHLORHEXIDINE AND IODOPHORAM ON STANDARD MICROBIAL STRAINS

The problem of treatment and prevention infectious-inflammatory post extraction complications in modern surgical dentistry are still challenging, despite the great advances this field. Many etiological factors identified as contributing to development such complications, but at present scientists paying much attention infectious factor, which is associated with microflora tooth socket after removal. According literature, most common post-extraction complication during an outpatient appointment alveolitis, accounts for 1-35% all cases extraction. To combat factor dental surgeons apply topical antiseptics a broad spectrum action iodoform chlorhexidine. As antiseptic drug oral inflammatory domestic antiseptic, Decasan, based on decamethoxine, becoming more widely applied. Previous studies have shown that has antimicrobial effect against gram-positive gram-negative, aerobic anaerobic bacteria; requires further in-depth its properties, could be applied practice treat prevent complications. Chlorhexidine bigluconate cationic biguanide. Penetrating into intracellular membranes bacteria, it impedes oxygen consumption leads death bacterial cells. This used practice. Treatment alveolitis carried out by using standard method, namely tamponade combination other medicines. Iodoform (triiodomethane) yellow crystalline substance strong characteristic odor, practically insoluble water. In dentistry, powder form, or combined pastes. purpose vitro study investigate properties chlorhexidine museum microbial strains. Materials methods. Museum strains Staphylococcus aureus ATCC 25923, epidermidis 14990, Enterococcus faecalis 29212, Esherichia coli 25922, Candida albicans 10231, obtained from L.V. Gromashevsky Institute Epidemiology Infectious Diseases, National Academy Medical Sciences Ukraine, were studied cultures microorganisms. decasan, was assessed quantitative method serial dilutions broth agar according order №167, dated 5.04.2007 On approval guidelines “Determination sensitivity microorganisms antibacterial drugs". Conclusion. data obtained, decasan demonstrate higher bacteriostatic bactericidal concentration thousands times lower than iodoform.